: relating to, being, or causing physiological changes in the body (such as an increase in heart rate or dilation of bronchi) in response to stress
epinephrine is a fight-or-flight hormone
a fight-or-flight reaction

Examples of fight-or-flight in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Oxytocin shifts your body out of fight-or-flight mode. Laura Kiniry, Popular Science, 17 June 2026 The defense will argue Gormley went for the Taser, exposing its pistol grip and triggering a fight-or-flight response in Harrison, who believed his life was in danger, Winter told jurors. Nate Gartrell, Mercury News, 16 June 2026 Stress Hormones Put Your Body in Fight-or-Flight Response The body's fight-or-flight response can affect the entire body, including your blood pressure. Angela Ryan Lee, Verywell Health, 11 June 2026 The sympathetic nervous system, colloquially known as fight-or-flight, releases hormones and engages nerves quickly and broadly; the parasympathetic nervous system, referred to as rest-and-digest, is slower and more targeted. Charlotte Harpur, New York Times, 3 June 2026 See All Example Sentences for fight-or-flight

Word History

First Known Use

1973, in the meaning defined above

Time Traveler
The first known use of fight-or-flight was in 1973

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Cite this Entry

“Fight-or-flight.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/fight-or-flight. Accessed 24 Jun. 2026.

Medical Definition

fight-or-flight

adjective
ˌfī-tər-ˈflīt
: relating to, being, or causing physiological changes in the body (such as an increase in heart rate or dilation of bronchi) in response to stress
the fight-or-flight response
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